Platform

The overall objective of the INCEPT research programme is to continuously develop a framework testing many interventions used in intensive care units (ICU) to the benefit of the sickest patients in the hospital, their relatives, and society.

The core of the programme is an adaptive, domain-based platform trial assessing commonly used interventions in adult acutely admitted ICU patients.

A platform trial focuses on a disease or a setting; thus, the overarching design does not focus on a single intervention. By running a platform trial, we can continuously enroll many ICU patients in Denmark and other countries and randomly allocate them to multiple interventions nested in different domains. INCEPT has no end date and is as such a lasting, common structure for valid improvements in ICU.

The work unfolds in five overarching working groups:

• Stakeholder involvement
• Methods
• Data infrastructure
• Funding
• Clinical domains

To ensure transparency and disseminate what we learn, we seek to publish all our finding and work. See our Publications library for a complete list.